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Tag: CYP2D6 interaction

Tamoxifen and SSRIs: What You Need to Know About Drug Interactions and Breast Cancer Risk

Tamoxifen and SSRIs: What You Need to Know About Drug Interactions and Breast Cancer Risk

Jan, 10 2026

Tamoxifen relies on CYP2D6 to become active. Some SSRIs block this enzyme, lowering endoxifen levels. But do they actually raise cancer risk? Evidence shows most SSRIs are safe - and untreated depression is the real danger.

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